BMP內(nèi)皮細(xì)胞調(diào)節(jié)蛋白抗體
規(guī)格：1mg/1ml
英文名： BMPER
別名： BMP binding endothelial regulator; BMP binding endothelial regulator precursor protein; Bone morphogenetic protein binding endothelial cell precursor derived regulator; CRIM3; Crossveinless 2; CV 2; C
分子量： 72kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BMPER
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
細(xì)胞定位：分泌型蛋白
BMP內(nèi)皮細(xì)胞調(diào)節(jié)蛋白抗體產(chǎn)品介紹：background: This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011]. BMPER is a BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, and may play a role in endothelial cell differentiation by modulating local BMP activity. It may also regulate BMP responsiveness in osteoblasts BMP內(nèi)皮細(xì)胞調(diào)節(jié)蛋白抗體and chondrocytes. Subunit: Interacts with BMP4. Subcellular Location: Secreted. Tissue Specificity: Highly expressed in lung, and brain and also in primary chondrocytes. Similarity: Contains 1 TIL (trypsin inhibitory-like) domain. Contains 5 VWFC domains.BMP內(nèi)皮細(xì)胞調(diào)節(jié)蛋白抗體 Contains 1 VWFD domain. Database links: UniProtKB/Swiss-Prot: Q8N8U9.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
BMP內(nèi)皮細(xì)胞調(diào)節(jié)蛋白抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：心血管 細(xì)胞生物 **學(xué) 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 生長因子和** 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 內(nèi)皮細(xì)胞
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid