黑色素瘤相關(guān)抗原B2抗體
規(guī)格：1mg/1ml
英文名： MAGEB2
別名： Cancer/testis antigen 3.2; CT3.2; DAM6; DSS AHC critical interval MAGE superfamily 6; DSS/AHC critical interval gene, from MAGE superfamily, 6; MAGE B2 antigen; MAGE XP 2; Mage-b2; Mage-rs2; melanoma
分子量： 35kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MAGEB2
交叉反應(yīng)：Human,
細胞定位：
黑色素瘤相關(guān)抗原B2抗體產(chǎn)品介紹：background: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]. Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3黑色素瘤相關(guān)抗原B2抗體 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Subunit: Interacts with TRIM28. Tissue Specificity: Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types. Similarity: Contains 1 MAGE domain. Gene ID: 4113 Database links: Entrez Gene: 4113 Human Omim: 300098 Human黑色素瘤相關(guān)抗原B2抗體 SwissProt: O15479 Human Unigene: 113824 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
黑色素瘤相關(guān)抗原B2抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤 腫瘤細胞生物標志物
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid